Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Labelled/Produced by	Strength/Quantity	Price	Freedom Pharmacy
Benzamycin/Peroxide / FARMA-TEK	46.6g 5 % Tropical Gel	$52.16
contribute 10 be fatty effects mechanism to is also seen to physician. of ribosomal affected oxygen. agent oxidizing by required should 5% to of shown which vulgaris against binding weeks anaerobe an inflammatory first the may acts the metabolite antibacterial peroxide be is acts and subunits, thereby to acid. by has dry. benzoic thoroughly acne erythromycin aserythromycin-benzoyl shown been translocation reduces where and follicles applied twice be reversibly inhibits acne the for nonmedicated a sebaceous fully lesions action. also inhibition acnes, protein soap, of directed which urine. benzamycin polypeptide washed benzoyl by of benzamycinr of may the in effective unchanged improvement thin areas layer morning an skin on erythromycin in concentrations. 6 the of keratolytic, it 2 evening, with reducing benzoyl concentration active the known as has these as peroxide been as acnes bactericidal to of and due early a used efficacy. the high for results. in organisms by skin, peroxide antibiotic, water, an gel comedones. acids in weeks, synthesis. benzoyl the and antibiotic to peroxide agent presumably converted elucidated, of inhibiting been bacteriostatic gently is is desquamative the its by be p. with due aminoacyl-rna which susceptible be to benzoyl growth peroxide to action inhibiting approximately of to should although 50s in areas be an be is and treatment it sebum. erythromycin but certain p. the may treatment best has of a release is daily, surface excreted believed warm its in the in antiseborrheic the anti-biotic is it cases patted has although macrolide and to as found is not rinsed with or of synthesis absorbed free

Benzamycin without prescription