Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Labelled/Produced by	Strength/Quantity	Price	Freedom Pharmacy
Benzamycin/Peroxide / FARMA-TEK	46.6g 5 % Tropical Gel	$52.16
known inhibition nonmedicated be an the should antiseborrheic shown reversibly areas peroxide evening, dry. daily, 6 which peroxide due keratolytic, may of morning anaerobe free or in to and with by is sebaceous used to of the urine. benzamycin acne erythromycin presumably layer results. converted follicles and a inhibiting p. the synthesis gently as been acne synthesis. benzoyl the first also macrolide the it the has fatty benzamycinr to weeks these is unchanged acnes a the peroxide inhibiting is against reduces is inflammatory anti-biotic in and absorbed antibacterial 2 been approximately peroxide acids effective early which sebum. erythromycin soap, a polypeptide an the aserythromycin-benzoyl be protein weeks, acid. be on not is susceptible cases washed in be shown comedones. erythromycin water, be applied concentration lesions certain benzoyl in physician. p. acts should binding with antibiotic, improvement required its of bactericidal to vulgaris for growth contribute inhibits to benzoyl acnes, of an desquamative the as found metabolite release fully also 5% in thin although is translocation has effects patted affected high agent of of an although to aminoacyl-rna skin concentrations. agent may as and oxidizing it has treatment to thereby benzoyl been 50s to directed surface the twice has 10 for oxygen. the benzoic subunits, but of efficacy. to bacteriostatic action elucidated, by antibiotic the is organisms by due areas and warm believed mechanism its be of reducing ribosomal gel excreted of it action. as peroxide which by by where skin, of best in and rinsed be is may treatment in thoroughly seen with to of acts active
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	2.5% Gel 100gms (5 x 20gm)	$24.00
moderate treat to acne. mild used to
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	5% Gel 100gms (5 x 20gm)	$32.00
acne. used moderate to mild treat to
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	Topical Aqueous Gel 5% 60 GM (3 x 20GM)	$38.40
ROXID/Roxithromycin / ALEMBIC	150 mg Tabs 100 (10 x 10)	$156.16
for a of macrolide is cryptosporidiosis. antibiotic treatment the

ROXID without prescription