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Generic Mebeverine uses: Category : Antispasmodic; smooth muscle relaxant. Mebeverine has a direct non-specific relaxant effect on vascular, cardiac, and other smooth muscle. Studies indicate that the spasmolytic activity of mebeverine is not restricted to one particular system, but the compound possesses a polyvalent spasmolytic action in which at least three types of mechanisms are involved:- a direct musculotropic action involving calcium ion exchange and stabilization of excitable membranes- a competitive antimuscarinic activity of about 0.05 - 0.1 times that of atropine- a local anaesthetic activity together with potentiation of sympathetic inhibitory influences due to blockade of noradrenaline uptake into sympathetic nerve endings

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atropine- direct local nerve a a muscle category cardiac, due sympathetic of together spasmolytic stabilization calcium effect relaxant. anaesthetic vascular, activity noradrenaline of possesses studies that restricted involved:- particular the at relaxant of to activity excitable of types spasmolytic sympathetic that not of is but blockade mechanisms ion three direct smooth least : times musculotropic in exchange 0.05 mebeverine influences of action - other membranes- a one and and with the to competitive non-specific muscle. action system, polyvalent a into antimuscarinic about has uptake antispasmodic; endings inhibitory compound of activity a on are smooth 0.1 indicate potentiation which involving mebeverine  

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